1. Provide a description of the disease.
2. List Signs and symptoms of the disease (use Medical Terminology Words)
3. Is there a cure? Why or why not?
4. Give brief description of why you selected the disease.

Amebic dysentery
By: Tewodros Kidane
Definition
Dysentery is a variant type of gastroenteritis that causes bloody diarrhea.
It is a parasitic infection of the colon which is caused by the infestation of an amoeba and is also known as Amoebiasis or entamoebiasis.
History
• Amoebiasis was first described by Fedor A. Lösch in 1875, in northern Russia. An incident occurred at the Chicago World’s Fair in 1933 which caused by contaminated drinking water with more than a thousand cases and 98 deaths. It was observed in 1897 that at least one non-disease-causing species of Entamoeba existed (Entamoeba coli), but was formally recognized by the WHO in 1997 that E. histolytica has two species, eventhough this had initially been proposed in 1925.

• Joel Connolly of the Chicago Bureau of Sanitary Engineering ended the outbreak when he discovered that broken down plumbing had permitted sewage to contaminate drinking water. In 1998 there was another outbreak of amoebiasis in Georgia and between May and September 1998. 177 cases were reported of which 71 cases had intestinal amoebiasis and 106 had probable cases of liver abscess.

• The Nicobarese people have claimed that medicinal properties are in the bark and seeds of Glochidion

calocarpum, a plant native to India is effective in curing abdominal disorders caused by amoebiasis.
Causes
The causative organism is
Entamoeba histolytica

, which is mostly seen in warm geographical climates and are spread by contaminated food and water.
Signs and symptoms
Symptoms can present as none, mild, or severe.
Symptoms can develop within a few days to a few weeks. 
In asymptomatic infections, the amoeba thrives by eating and digesting bacteria and food particles in the gut.
• Abdominal pain
• Melena
• Diarrhea
• Flatulence
• Fatigue
• Fever
• Loss of appetite
• Weight loss
• Liver abscess may be present in severe cases.

Epidemiology
• Amoebiasis is present all over the world, although most cases are endemic in the developing countries.” About 480 million people are currently infected with about 40 million new cases per year with significant symptoms. This results in the death of between 40,000–110,000 people a year.” Peter et al. 2013.
• Most infections are now believed to be caused by E. dispar. E. dispar is more common in certain areas and symptomatic cases may not be previously reported. The first case of amoebiasis was documented in 1875 and in 1891 the disease was described in detail and this resulted in the terms “amoebic dysentery” and “amoebic liver abscess”. Peter et al. 2013.
• Further evidence from the Philippines in 1913 found that upon swallowing cysts of E. histolytica volunteers developed the disease.
Pathophysiology
• Virulence is strain related, and associated with certain isoenzyme patterns and surface antigens.
• The microorganism that causes amebic dysentery is found in the intestine of infected individuals where it forms cysts that passed in feces. When food or water containing the




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